Clinical Research on Stroke
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We have a special interest in:
- the impact of cardiac markers (Troponin, heart rate, heart rate variability) on stroke outcome
- the impact of biomarkers (e.g. Troponin, Cholesterol-levels) and of drugs (e.g. statins) on complications following thrombolysis in particular (e.g. intracranial bleeding) and on complications following stroke in general (e.g. clinically silent new DWI-lesions (silent stroke), clinically manifest recurrent stroke, pneumonia)
- translation and validation of scores and instruments (e.g. standardized questionnaires)
- process analysis of pre- and intrahospital delay (Berlin Acute Stroke Study)
Selected Publications
- Authors:Scheitz JF, Seiffge DJ, Tütüncü S, Gensicke H, Audebert HJ, Bonati LH, Fiebach JB, Tränka C, Lyrer PA, Endres M, Engelter ST, Nolte CH
Journal:Stroke Year:2014; Volume:45:Pages:509-14.
Title:Dose-related effects of statins on symptomatic intracerebral hemorrhage and outcome after thrombolysis for ischemic stroke - Authors:Tütüncü S, Ziegler AM, Scheitz JF, Slowinski T, Rocco A, Endres M, Nolte CH
Journal:Stroke Year:2013; Volume:44Issue:(11):Pages:3217-9.
Title:Severe renal impairment is associated with symptomatic intracerebral hemorrhage after thrombolysis for ischemic stroke - Authors:Nolte C.H., Albach F.N. Albach FN, Heuschmann P.U., Brunecker P, Villringer K., Endres M., Fiebach JB
Journal:Cerebrovascular Diseases Year:2012; Volume:33:Pages:248-254.
Title:Silent new DWI-lesions within the first week after stroke - Authors:Usnich T, Albach FN, Brunecker P, Fiebach JB, Nolte CH
Journal:Stroke Year:2012; Volume:43:Pages:2654-8.
Title:Incidence of new diffusion-weighted imaging lesions outside the area of initial hypoperfusion within 1 week after acute ischemic stroke - Authors:Scheitz JF, Endres M, Mochmann HC, Audebert HJ, Nolte CH
Journal:Int J Cardiol Year:2012; Volume:157:Pages:239-42.
Title:Frequency, determinants and outcome of elevated troponin in acute ischemic stroke patients - Authors:Koennecke H.C., Belz W., Berfelde D., Endres M., Fitzek S., Hamilton F., Kreitsch P., Mackert B.M., Nabavi D.G., Nolte C.H., Pöhls W., Schmehl I., Schmitz B., von Brevern M., Walter G., Heuschmann P.U. & For the Berlin Stroke Register Investigators
Journal:Neurology Year:2011; Volume:77:Pages:965-972.
Title:Factors influencing in-hospital mortality and morbidity in patients treated on a stroke unit - Authors:Müller-Nordhorn J, Wegscheider K, Nolte CH, Jungehülsing GJ, Rossnagel K, Reich A, Roll S, Villringer A, Willich SN
Journal:Arch Intern Med Year:2009; Volume:169:Pages:1484-90.
Title:Population-based intervention to reduce prehospital delays in patients with cerebrovascular events